![]() ![]() 16 Numerous associations with other possible triggers have been reported 2 yet, none of these correlations have been validated in a nationwide database. 14, 15 Migraines and epilepsy have also been implicated as potential correlates of TGA. 10 – 13 More recent studies have focused on the discovery that a large percentage of TGA patients have jugular venous insufficiency. High-resolution brain MRI of TGA patients suggests diffusion restriction in the hippocampi. ![]() Because of the implicated loss of declarative memory, ischemia in bilateral hippocampi has been suggested as a possible cause. 9 Past studies have attempted to correlate TGA to vascular risk factors, migraine, and epilepsy, with variable results. 7, 8ĭespite the general acceptance of TGA as a clinical entity, its etiology has yet to be determined. 4 – 6 The average age of onset has ranged between 50–80 years, with an incidence of approximately 5–11 per 100,000 per year. Previous studies on TGA have been inconsistent regarding sex prevalence. 1 – 3 Though generally self-limited with rare recurrences, this striking presentation has spurred efforts to link TGA to more consequential and treatable conditions. Transient global amnesia (TGA) is an uncommon amnestic syndrome characterized by a combined anterograde and retrograde amnesia of sudden onset. All minority populations showed a lower rate of diagnosis that fell short of statistical significance. Patients with migraines and patients classified as Caucasian had higher odds of being diagnosed with TGA. ![]() TGA was associated with lower hospital charges ($14,242 versus $21,319), shorter hospital stays (mean days: 2.49 versus 4.72 ), and routine hospital discharges (91.4% versus 74.5%). The odds of being diagnosed with TGA was lower among African Americans and Hispanics as well as among patients classified as Asian/Other, compared with Caucasians. Similarly, patients with TGA were more likely to have hypertension, precerebral disease, and hyperlipidemia. Patients with migraines were 5.98 times more likely to also have a diagnosis of TGA compared with patients without migraines. Descriptive and survey logistic regression analyses were conducted and adjusted for influence of comorbidities, demographic characteristics, and hospitalization-related factors. Data were obtained from the Nationwide Inpatient Sample using ICD-9 and procedure codes. The purpose of this article was to explore sex- and race-specific variables and comorbidities associated with transient global amnesia (TGA) using a nationally representative database. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |